Torin 1-mTOR inhibitor enhances cellular proliferation in NT-1 tobacco suspension cell cultures
Torin 1, is an ATP-competitive kinase inhibitor targeting rapamycin (TOR) which inhibits the signaling of TOR and S6K kinase in mammals and plants. During kinetics growth of tobacco cultures suspended in NT-1, Torin 1 inhibits the early growth and later enhanced the cellular proliferation during exponential growth by means of an increased expression of E2F1 and cyclin B.
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